Code: EU11680
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Description Velcade 3.5 mg Janssen-Cilag
Specification Velcade 3.5 mg Janssen-Cilag
Features
Active substance
Bortezomib
Also known as
PS-341
Blood pressure
Can cause hypotension or hypertension
Chemical name
[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic acid
Dosage (medical)
Typically 1.3 mg/m^2 body surface area, administered as an intravenous injection twice a week for two weeks, followed by a 10-day rest period
Dosage (sports)
Not applicable
Effects
Induces apoptosis and inhibits cell growth and proliferation
Formula
C19H25BN4O4
Half-life
9 to 15 hours
Hepatotoxicity
Low
Lab Test
Blood counts, liver enzymes, and renal function tests should be monitored
Main action
Inhibits the 26S proteasome
Side effects
Peripheral neuropathy, fatigue, gastrointestinal disturbances, thrombocytopenia, neutropenia, anemia, pyrexia
Storage conditions
Store at 2В°C to 8В°C (36В°F to 46В°F) in original package to protect from light
Substance class
Proteasome inhibitor
Trade name
Velcade
Use in sports
None
WAREHOUSE
International Warehouse 2
Water Retention
Minimal
Manufacturer
Janssen-Cilag
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